Cholesterol Diagnostics

£81.00

1880

Elevated blood cholesterol has been established as a serious risk factor for coronary heart disease and stroke which are leading causes of death in the United States. A disease known as familial hypercholesterolemia (FH) causes an increase in blood levels of the "bad" form of cholesterol, known as low density lipoprotein (LDL). In this electrophoresis experiment, a simulated genetic test for hypercholesterolemia is demonstrated in which patients are tested for a DNA polymorphism linked to the FH gene.

• Discover how doctors identify genetic diseases using molecular technologies
• Explore the genetics of familial hypercholesterolemia
• Perform agarose gel electrophoresis to separate differently-sized DNA molecules
• Load, run, analyze, and size control samples and three patient samples to determine whether patients are normal, heterozygous, or homozygous for the FH mutation.

Kit Includes:

Instructions, Ready-to-Load QuickStrip™ DNA Samples, UltraSpec-Agarose™, Electrophoresis Buffer (50X), Practice Gel Loading Solution, FlashBlue™ DNA Stain.

All You Need:

DNA Electrophoresis, Micropipettes: 5-50 µl (Optional), White Light Box, & Microwave or Hot Plate.

*PLEASE NOTE WE ONLY SUPPLY CHEMICALS TO EDUCATIONAL ESTABLISHMENTS *

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Cholesterol Diagnostics

£81.00

£81.00

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